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answered, "I believe the common ingredient is quinine, and I do not believe that does any physical harm whatever" (p. 136). Continuing, he said: "As regards the direct effect of quinine pessaries, I have never seen a case in which I thought any damage had been done" (p. 138).

As already noted, it appears to me that the quinine is by no means the only thing which gives security, and that the quantity of grease is sufficient in itself to be a fair safeguard even if there were no quinine to secure immunity.

There are many formulæ for the formation of such suppositories, and some contain quinine only, others a mixture of chemicals. An American medical practitioner recommends the following:—

I think this formula needlessly difficult to weigh out.

A formula devised by another American practitioner for use by his poor patients who desired to make the suppositories themselves, is as follows:—