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CHAPTER FIVE

powder, it is sometimes enclosed in capsules to be inserted in the vagina; but the method is not particularly reliable as the powder does not get well distributed.

(11b) Quinine as an ointment.

Quinine mixed with a fatty base in the form of ointment is prepared, and is sold by chemists for the special purpose of use during coitus. It may be smeared thickly on an ordinary sponge or on a pad of cotton wool. It is also used for surrounding the caps (see p. 143) and for smearing over them. It should, however, be noted that the use of grease tends to rot the rubber. The use of ointment is a matter of individual choice, some relying upon it and finding it satisfactory, others never making use of it at all.

(11c) Quinine as a pessary or suppository contained in a matrix of low melting point, such as cocoa butter or gelatine.

The commonest form in which quinine is used is as a vaginal suppository in which quinine sulphate, usually with salicylic acid, quinine salicylate, or other form of quinine, are included in a small quantity of cocoa-butter (see formulæ p. 108). The form of suppository is generally that of a flattened, ellipsoid cone, rendering insertion easy, and

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