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island of Bombay. Clearly, therefore, it is hardly correct to suppose that cholera is only endemic in the valley of the Ganges: it is more than probable that the disease is endemic in all large towns along the seaboard of British India, including Chittagong and parts of the Pegu division.[1] I have already referred to its frequent appearance in the ceded districts of Madras, of which Bellary is the capital, and which includes the table land between the Eastern and Western Ghauts, having an elevation of some 1600 feet above the level of the sea. Cholera was doubtless endemic in these districts in 1833-34, and remains so up to the present day, breaking out year after year during the annual festival at Humpi. From these districts, passing northward, we come to those of "Saugor and Nagode, which belong to the Gangetic basin,"[2] and in which cholera appears to a greater or less extent twice a year. We shall probably not be far wide of the mark if we draw an imaginary line to the north-east through Saugor, Allahabad, and Gorruckpore, to the foot of the Himalayas; throughout the whole of the plains to the east of this hne cholera is endemic, the intensity of the disease increasing as we approach the seaboard of the Bay of Bengal, the cities of Dacca and Calcutta being pre-eminently the stronghold of this terrible malady. Cholera is less frequently met with as we advance to the north-west and west from the line I have above indicated, until the disease may with certainty be said not to be endemic in the Punjab, Rajpootana, and Sind. But along the valley of the Nerbudda and Tafty rivers, and throughout a very